AFF4 Antibody
Product Sizes
50ug
£305.00
OACA09722-50UG
100ug
£463.00
OACA09722-100UG
About this Product
- SKU:
- OACA09722
- Additional Names:
- AF4/FMR2 family member 4;AF5Q31;ALL1-fused gene from chromosome 5q31 protein;CHOPS;major CDK9 elongation factor-associated protein;MCEF.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Key component of the super elongation complex (SEC); a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex; AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins (ELL; ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus; the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.
- Gene Details:
- AF4/FMR2 family member 4
- Host:
- Rabbit
- Immunogen:
- Recombinant Human AF4/FMR2 family member 4 protein (77-334AA)
- Isotype:
- IgG
- Protein Details:
- AF4/FMR2 family member 4
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
