C7ORF49 Antibody
Product Sizes
50ug
£305.00
OACA09712-50UG
100ug
£463.00
OACA09712-100UG
About this Product
- SKU:
- OACA09712
- Additional Names:
- C7orf49;cell cycle regulator of non-homologous end joining;modulator of retrovirus infection homolog;MRI;MRI-2.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Isoform 1: Cell-cycle-specific inhibitor of classical non-homologous end joining (NHEJ) of DNA double-strand break (DSB) repair during the S and G2 phases (PubMed:28959974). Acts as a regulator of DNA repair pathway choice by specifically inhibiting classical NHEJ during the S and G2 phases; thereby promoting error-free repair by homologous recombination during cell cycle phases when sister chromatids are present (PubMed:28959974). Preferentially protects single-stranded overhangs at break sites by inhibiting classical NHEJ; thereby creating a local environment that favors homologous recombination (PubMed:28959974). Acts via interaction with XRCC5/Ku80 and XRCC6/Ku70; interaction restricted during the S and G2 phases only (PubMed:28959974). Molecular mechanisms governing classical NHEJ inhibition via interaction with XRCC5/Ku80 and XRCC6/Ku70 are unknown (PubMed:28959974). May act as a regulator of proteasome (By similarity).
- Gene Details:
- cell cycle regulator of NHEJ
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Cell cycle regulator of non-homologous end joining protein (1-157AA)
- Isotype:
- IgG
- Protein Details:
- Cell cycle regulator of non-homologous end joining
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
