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Antibodies

BCL11B Antibody

Product Sizes
50ug
£305.00
OACA09701-50UG
100ug
£463.00
OACA09701-100UG
About this Product
SKU:
OACA09701
Additional Names:
ATL1;ATL1-alpha;ATL1-beta;ATL1-delta;ATL1-gamma;B cell CLL/lymphoma 11B;B-cell CLL/lymphoma 11B;B-cell CLL/lymphoma 11B (zinc finger protein);B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein;B-cell lymphoma/leukaemia 11B;B-cell lymphoma/leukemia 11B;BCL-11B;BCL11B; BAF complex component;BCL11B/TRDC fusion;COUP-TF-interacting protein 2;CTIP2;CTIP-2;hRit1;hRIT1-alpha;IDDFSTA;IMD49;radiation-induced tumor suppressor gene 1 protein;RIT1;SMARCM2;zinc finger protein hRit1 alpha;ZNF856B.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals. Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of the receptors CCR7 and CCR9; which direct the movement of progenitor cells from the bone marrow to the thymus (PubMed:27959755). Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4(+) T-lymphocytes (PubMed:16809611). Tumor-suppressor that represses transcription through direct; TFCOUP2-independent binding to a GC-rich response element (By similarity). May also function in the P53-signaling pathway (By similarity).
Gene Details:
BAF chromatin remodeling complex subunit BCL11B
Host:
Rabbit
Immunogen:
Recombinant Human B-cell lymphoma/leukemia 11B protein (500-550AA)
Isotype:
IgG
Protein Details:
B-cell lymphoma/leukemia 11B
Purity:
>95%
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody