BRD7 Antibody
Product Sizes
50ug
£305.00
OACA09678-50UG
100ug
£463.00
OACA09678-100UG
About this Product
- SKU:
- OACA09678
- Additional Names:
- 75 kDa bromodomain protein;BP75;bromodomain-containing protein 7;CELTIX1;NAG4;protein CELTIX-1;SMARCI1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- Varies by lot. See vial for concentration.
- Extra Details:
- Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters; leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382'; and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase.
- Gene Details:
- bromodomain containing 7
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Bromodomain-containing protein 7 protein (601-651AA)
- Isotype:
- IgG
- Protein Details:
- Bromodomain-containing protein 7
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
