PIF1 Antibody
Product Sizes
50ug
£305.00
OACA09676-50UG
100ug
£463.00
OACA09676-100UG
About this Product
- SKU:
- OACA09676
- Additional Names:
- ATP-dependent DNA helicase PIF1;C15orf20;DNA repair and recombination helicase PIF1;petite integration frequency 1;PIF;PIF1 5'-to-3' DNA helicase homolog;PIF1/RRM3 DNA helicase-like protein.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures; preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation; de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.
- Gene Details:
- PIF1 5'-to-3' DNA helicase
- Host:
- Rabbit
- Immunogen:
- Recombinant Human ATP-dependent DNA helicase PIF1 protein (125-360AA)
- Isotype:
- IgG
- Protein Details:
- ATP-dependent DNA helicase PIF1
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
