KAT2B Antibody
Product Sizes
50ug
£305.00
OACA09633-50UG
100ug
£463.00
OACA09633-100UG
About this Product
- SKU:
- OACA09633
- Additional Names:
- CAF;CREBBP-associated factor;histone acetylase PCAF;histone acetyltransferase KAT2B;histone acetyltransferase PCAF;K(lysine) acetyltransferase 2B;Lysine acetyltransferase 2B;P/CAF;p300/CBP-associated factor;PCAF;spermidine acetyltransferase KAT2B.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4); and also with nucleosome core particles. Also acetylates non-histone proteins; such as ACLY; PLK4 and TBX5. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Involved in heart and limb development by mediating acetylation of TBX5; acetylation regulating nucleocytoplasmic shuttling of TBX5 (PubMed:29174768). Acts as a negative regulator of centrosome amplification by mediating acetylation of PLK4 (PubMed:27796307).
- Gene Details:
- lysine acetyltransferase 2B
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Histone acetyltransferase KAT2B protein (767-832AA)
- Isotype:
- IgG
- Protein Details:
- Histone acetyltransferase KAT2B
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
