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Antibodies

KDM1B Antibody

Product Sizes
50ug
£305.00
OACA09629-50UG
100ug
£463.00
OACA09629-100UG
About this Product
SKU:
OACA09629
Additional Names:
AOF1;C6orf193;flavin-containing amine oxidase domain-containing protein 1;LSD2;lysine (K)-specific demethylase 1B;lysine-specific histone demethylase 1B;lysine-specific histone demethylase 2.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Histone demethylase that demethylates 'Lys-4' of histone H3; a specific tag for epigenetic transcriptional activation; thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4'; mono-; di- or tri-methylated 'Lys-9'; mono-; di- or tri-methylated 'Lys-27'; mono-; di- or tri-methylated 'Lys-36' of histone H3; or on mono-; di- or tri-methylated 'Lys-20' of histone H4.
Gene Details:
lysine demethylase 1B
Host:
Rabbit
Immunogen:
Recombinant Human Lysine-specific histone demethylase 1B protein (451-544AA)
Isotype:
IgG
Protein Details:
Lysine-specific histone demethylase 1B
Purity:
>95%
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody