RUNX1T1 Antibody
Product Sizes
50ug
£305.00
OACA09570-50UG
100ug
£463.00
OACA09570-100UG
About this Product
- SKU:
- OACA09570
- Additional Names:
- acute myelogenous leukemia 1 translocation 1; cyclin-D related;AML1-MTG8;AML1T1;CBFA2T1;CDR;core-binding factor; runt domain; alpha subunit 2; translocated to; 1; cyclin D-related;Cyclin-D-related protein;eight twenty one protein;ETO;MTG8;myeloid translocation gene on 8q22;protein CBFA2T1;Protein ETO;Protein MTG8;runt related transcription factor 1; translocated to; 1 (cyclin D related);RUNX1 translocation partner 1;zinc finger MYND domain-containing protein 2;ZMYND2.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562; PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453). Can repress transactivation mediated by TCF12 (PubMed:16803958). Acts as a negative regulator of adipogenesis (By similarity). The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal (PubMed:23812588).
- Gene Details:
- RUNX1 partner transcriptional co-repressor 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Protein CBFA2T1 protein (416-525AA)
- Isotype:
- IgG
- Protein Details:
- Protein CBFA2T1
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
