IKZF1 Antibody
Product Sizes
50ug
£305.00
OACA09552-50UG
100ug
£463.00
OACA09552-100UG
About this Product
- SKU:
- OACA09552
- Additional Names:
- CLL-associated antigen KW-6;CVID13;DNA-binding protein Ikaros;Hs.54452;IK1;IKAROS;ikaros family zinc finger protein 1;LyF-1;LYF1;lymphoid transcription factor LyF-1;PPP1R92;PRO0758;protein phosphatase 1; regulatory subunit 92;zinc finger protein; subfamily 1A; 1 (Ikaros);ZNFN1A1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Transcription regulator of hematopoietic cell differentiation (PubMed:17934067). Binds gamma-satellite DNA (PubMed:17135265; PubMed:19141594). Plays a role in the development of lymphocytes; B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes; NuRD and BAF (SWI/SNF); in a single complex (PYR complex); to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity). Function is isoform-specific and is modulated by dominant-negative inactive isoforms (PubMed:17135265; PubMed:17934067).
- Gene Details:
- IKAROS family zinc finger 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DNA-binding protein Ikaros protein (1-265AA)
- Isotype:
- IgG
- Protein Details:
- DNA-binding protein Ikaros
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
