ARHGEF5 Antibody
Product Sizes
50ug
£305.00
OACA09549-50UG
100ug
£463.00
OACA09549-100UG
About this Product
- SKU:
- OACA09549
- Additional Names:
- ephexin3;ephexin-3;GEF5;guanine nucleotide regulatory protein TIM;oncogene TIM;P60;p60 TIM;Rho guanine nucleotide exchange factor (GEF) 5;rho guanine nucleotide exchange factor 5;TIM;TIM1;transforming immortalized mammary oncogene.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB; weakly activates RHOC and RHOG and shows no effect on RHOD; RHOV; RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration (By similarity).
- Gene Details:
- Rho guanine nucleotide exchange factor 5
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Rho guanine nucleotide exchange factor 5 protein (433-507AA)
- Isotype:
- IgG
- Protein Details:
- Rho guanine nucleotide exchange factor 5
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
