DNAJC3 Antibody
Product Sizes
50ug
£305.00
OACA09545-50UG
100ug
£463.00
OACA09545-100UG
About this Product
- SKU:
- OACA09545
- Additional Names:
- ACPHD;DnaJ (Hsp40) homolog; subfamily C; member 3;dnaJ homolog subfamily C member 3;endoplasmic reticulum DNA J domain-containing protein 6;ERdj6;ER-resident protein ERdj6;HP58;interferon-induced; double-stranded RNA-activated protein kinase inhibitor;P58;p58(IPK);P58IPK;PRKRI;protein kinase inhibitor of 58 kDa;protein kinase inhibitor p58;protein-kinase; interferon-inducible double stranded RNA dependent inhibitor.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress; hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70; it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
- Gene Details:
- DnaJ heat shock protein family (Hsp40) member C3
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DnaJ homolog subfamily C member 3 protein (277-496AA)
- Isotype:
- IgG
- Protein Details:
- DnaJ homolog subfamily C member 3
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
