TLR1 Antibody
Product Sizes
50ug
£305.00
OACA09489-50UG
100ug
£463.00
OACA09489-100UG
About this Product
- SKU:
- OACA09489
- Additional Names:
- CD281;rsc786;TIL;TIL. LPRS5;toll/interleukin-1 receptor-like protein;toll-like receptor 1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed:21078852). Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides; this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211). Acts via MYD88 and TRAF6; leading to NF-kappa-B activation; cytokine secretion and the inflammatory response.
- Gene Details:
- toll like receptor 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Toll-like receptor 1 protein (25-580AA)
- Isotype:
- IgG
- Protein Details:
- Toll-like receptor 1
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
