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Antibodies

ACOD1 Antibody

Product Sizes
50ug
£305.00
OACA09406-50UG
100ug
£463.00
OACA09406-100UG
About this Product
SKU:
OACA09406
Additional Names:
Aconitate decarboxylase;Aconitate decarboxylase 1;CAD;cis-aconitate decarboxylase;cis-aconitic acid decarboxylase;Immune-responsive gene 1 protein;immune-responsive gene 1 protein homolog;immunoresponsive 1 homolog;IRG1.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Concentration:
Varies by lot. See vial for concentration.
Extra Details:
Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
Gene Details:
aconitate decarboxylase 1
Host:
Rabbit
Immunogen:
Recombinant Human Cis-aconitate decarboxylase protein (57-257AA)
Isotype:
IgG
Protein Details:
Cis-aconitate decarboxylase
Purity:
>95%
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody