ERLIN2 Antibody
Product Sizes
50ug
£305.00
OACA09372-50UG
100ug
£463.00
OACA09372-100UG
About this Product
- SKU:
- OACA09372
- Additional Names:
- C8orf2;endoplasmic reticulum lipid raft-associated protein 2;epididymis secretory sperm binding protein;erlin-2;NET32;spastic paraplegia 18 (autosomal dominant);SPFH domain family; member 2;SPFH2;SPG18;stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1;4;5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:19240031; PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed:24217618).
- Gene Details:
- ER lipid raft associated 2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Erlin-2 protein (25-206AA)
- Isotype:
- IgG
- Protein Details:
- Erlin-2
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
