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Antibodies

ASIP Antibody

Product Sizes
50ug
£305.00
OACA09338-50UG
100ug
£463.00
OACA09338-100UG
About this Product
SKU:
OACA09338
Additional Names:
agouti signaling protein; nonagouti homolog;agouti switch protein;agouti-signaling protein;AGSW;AGTI;AGTIL;ASP;nonagouti homolog;SHEP9.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP; leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates; agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.
Gene Details:
agouti signaling protein
Host:
Rabbit
Immunogen:
Recombinant Human Agouti-signaling protein (23-112AA)
Isotype:
IgG
Protein Details:
Agouti-signaling protein
Purity:
>95%
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody