APOBEC3G Antibody
Product Sizes
50ug
£305.00
OACA09336-50UG
100ug
£463.00
OACA09336-100UG
About this Product
- SKU:
- OACA09336
- Additional Names:
- A3G;APOBEC-related cytidine deaminase;APOBEC-related protein 9;apolipoprotein B editing enzyme catalytic polypeptide-like 3G;apolipoprotein B mRNA editing enzyme cytidine deaminase;apolipoprotein B mRNA editing enzyme; catalytic polypeptide-like 3G;apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3G;ARCD;ARP9;ARP-9;bK150C2.7;CEM15;CEM-15;deoxycytidine deaminase;dJ494G10.1;DNA dC->dU editing enzyme;DNA dC->dU-editing enzyme APOBEC-3G;MDS019;phorbolin-like protein MDS019.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits potent antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription; it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA; leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome; along with a deamination-independent mechanism that works prior to the proviral integration; together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity also against simian immunodeficiency viruses (SIVs); hepatitis B virus (HBV); equine infectious anemia virus (EIAV); xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV). May inhibit the mobility of LTR and non-LTR retrotransposons.
- Gene Details:
- apolipoprotein B mRNA editing enzyme catalytic subunit 3G
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DNA dC->dU-editing enzyme APOBEC-3G protein (1-384AA)
- Isotype:
- IgG
- Protein Details:
- DNA dC->dU-editing enzyme APOBEC-3G
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
