IFNLR1 Antibody
Product Sizes
50ul
£316.00
OACA09130-50UL
100ul
£387.00
OACA09130-100UL
About this Product
- SKU:
- OACA09130
- Additional Names:
- class II cytokine receptor CRF2/12;CRF2/12;CRF2-12;cytokine receptor class-II member 12;cytokine receptor family 2 member 12;IFN-lambda receptor 1;IFN-lambda-R1;IFNLR;IL-28 receptor subunit alpha;IL-28R1;IL28RA;IL-28RA;IL-28R-alpha;interferon lambda receptor 1;interleukin 28 alpha receptor;interleukin 28 receptor A;interleukin 28 receptor; alpha (interferon; lambda receptor);interleukin or cytokine receptor 2;interleukin-28 receptor subunit alpha;LICR2;likely interleukin or cytokine receptor 2.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG); which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory; gastrointestinal; and reproductive tracts. Seems not to be essential for early virus-activated host defense in vaginal infection; but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium.
- Gene Details:
- interferon lambda receptor 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Interferon lambda receptor 1 protein (21-228AA)
- Isotype:
- IgG
- Protein Details:
- Interferon lambda receptor 1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
