ALCAM Antibody
Product Sizes
50ul
£316.00
OACA09078-50UL
100ul
£387.00
OACA09078-100UL
About this Product
- SKU:
- OACA09078
- Additional Names:
- Activated leukocyte cell adhesion molecule;CD166;CD166 antigen;MEMD.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6; as well as homotypic cell-cell contacts (PubMed:7760007; PubMed:15496415; PubMed:15048703; PubMed:16352806; PubMed:23169771; PubMed:24945728). Promotes T-cell activation and proliferation via its interactions with CD6 (PubMed:15048703; PubMed:16352806; PubMed:24945728). Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 (PubMed:15294938; PubMed:16352806). Mediates homotypic interactions with cells that express ALCAM (PubMed:15496415; PubMed:16352806). Required for normal hematopoietic stem cell engraftment in the bone marrow (PubMed:24740813). Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction (PubMed:23169771). Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions (PubMed:15496415; PubMed:23169771). Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis; required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation (By similarity). Promotes neurite extension; axon growth and axon guidance; axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity).
- Gene Details:
- activated leukocyte cell adhesion molecule
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CD166 antigen protein (28-180AA)
- Isotype:
- IgG
- Protein Details:
- CD166 antigen
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
