PIEZO1 Antibody
Product Sizes
50ul
£316.00
OACA09006-50UL
100ul
£387.00
OACA09006-100UL
About this Product
- SKU:
- OACA09006
- Additional Names:
- DHS;FAM38A;family with sequence similarity 38; member A;LMPH3;LMPHM6;membrane protein induced by beta-amyloid treatment;Mib;piezo-type mechanosensitive ion channel component 1;Protein FAM38A.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Pore-forming subunit of a mechanosensitive non-specific cation channel (PubMed:23479567; PubMed:23695678). Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER; most probably in its activated state; and subsequent stimulation of calpain signaling (PubMed:20016066). In the kidney; may contribute to the detection of intraluminal pressure changes and to urine flow sensing. Acts as shear-stress sensor that promotes endothelial cell organization and alignment in the direction of blood flow through calpain activation (PubMed:25119035). Plays a key role in blood vessel formation and vascular structure in both development and adult physiology (By similarity).
- Gene Details:
- piezo type mechanosensitive ion channel component 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Piezo-type mechanosensitive ion channel component 1 protein (2230-2420AA)
- Isotype:
- IgG
- Protein Details:
- Piezo-type mechanosensitive ion channel component 1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
