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Antibodies

NECTIN3 Antibody

Product Sizes
50ul
£316.00
OACA08940-50UL
100ul
£387.00
OACA08940-100UL
About this Product
SKU:
OACA08940
Additional Names:
CD113;CDW113;nectin 3;Nectin cell adhesion molecule 3;nectin-3;poliovirus receptor-related 3;poliovirus receptor-related protein 3;PPR3;PRR3;PVRL3;PVRR3.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins; such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions; including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface; resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
Gene Details:
nectin cell adhesion molecule 3
Host:
Rabbit
Immunogen:
Recombinant Human Nectin-3 protein (310-549AA)
Isotype:
IgG
Protein Details:
Nectin-3
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody