EIF3K Antibody
Product Sizes
50ul
£316.00
OACA08924-50UL
100ul
£387.00
OACA08924-100UL
About this Product
- SKU:
- OACA08924
- Additional Names:
- ARG134;eIF-3 p25;eIF-3 p28;EIF3-p28;EIF3S12;Eukaryotic translation initiation factor 3 subunit 12;eukaryotic translation initiation factor 3 subunit K;eukaryotic translation initiation factor 3; subunit 12;HSPC029;M9;MSTP001;muscle specific;muscle-specific gene M9 protein;PLAC24;PLAC-24;PRO1474;PTD001.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Component of the eukaryotic translation initiation factor 3 (eIF-3) complex; which is required for several steps in the initiation of protein synthesis (PubMed:17581632; PubMed:25849773; PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1; eIF-1A; eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation; including cell cycling; differentiation and apoptosis; and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
- Gene Details:
- eukaryotic translation initiation factor 3 subunit K
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Eukaryotic translation initiation factor 3 subunit K protein (1-218AA)
- Isotype:
- IgG
- Protein Details:
- Eukaryotic translation initiation factor 3 subunit K
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
