BLOC1S2 Antibody
Product Sizes
50ul
£316.00
OACA08729-50UL
100ul
£387.00
OACA08729-100UL
About this Product
- SKU:
- OACA08729
- Additional Names:
- 11 kDa centrosome associated protein;biogenesis of lysosome-related organelles complex 1 subunit 2;BLOC-1 subunit 2;BLOS2;BORCS2;CEAP;CEAP11;centrosomal 10 kDa protein;centrosome protein oncogene;Centrosome-associated protein.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Component of the BLOC-1 complex; a complex that is required for normal biogenesis of lysosome-related organelles (LRO); such as platelet dense granules and melanosomes (PubMed:15102850; PubMed:17182842). In concert with the AP-3 complex; the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex; in association with SNARE proteins; is also proposed to be involved in neurite extension (By similarity). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes; the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167). May play a role in cell proliferation (PubMed:15381421).
- Gene Details:
- biogenesis of lysosomal organelles complex 1 subunit 2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 2 protein (44-142AA)
- Isotype:
- IgG
- Protein Details:
- Biogenesis of lysosome-related organelles complex 1 subunit 2
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
