BVES Antibody
Product Sizes
50ul
£316.00
OACA08560-50UL
100ul
£387.00
OACA08560-100UL
About this Product
- SKU:
- OACA08560
- Additional Names:
- blood vessel epicardial substance;CARICK;HBVES;LGMD2X;LGMDR25;POP1;POPDC1;popeye domain-containing protein 1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells (PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading (By similarity). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated; at least in part; through cAMP-binding and; probably; by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density (PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.
- Gene Details:
- blood vessel epicardial substance
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Blood vessel epicardial substance protein (241-360AA)
- Isotype:
- IgG
- Protein Details:
- Blood vessel epicardial substance
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
