CALCOCO1 Antibody
Product Sizes
50ul
£316.00
OACA08431-50UL
100ul
£387.00
OACA08431-100UL
About this Product
- SKU:
- OACA08431
- Additional Names:
- calcium-binding and coiled-coil domain-containing protein 1;calphoglin;Cocoa;coiled-coil coactivator protein;coiled-coil leucine zipper coactivator 1;inorganic pyrophosphatase activator;PP13275;sarcoma antigen NY-SAR-3.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators; such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins; such as EP300; CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions (By similarity). In association with CCAR1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781).
- Gene Details:
- calcium binding and coiled-coil domain 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Calcium-binding and coiled-coil domain-containing protein 1 protein (462-691AA)
- Isotype:
- IgG
- Protein Details:
- Calcium-binding and coiled-coil domain-containing protein 1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
