ZBTB48 Antibody
Product Sizes
50ul
£316.00
OACA08411-50UL
100ul
£387.00
OACA08411-100UL
About this Product
- SKU:
- OACA08411
- Additional Names:
- GLI-Kruppel family member HKR3;HKR3;krueppel-related zinc finger protein 3;pp9964;telomere zinc finger-associated protein;telomeric zinc finger-associated protein;TZAP;zinc finger and BTB domain-containing protein 48;zinc finger protein 855;ZNF855.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Telomere-binding protein that acts as a regulator of telomere length (PubMed:28500257; PubMed:28082411). Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat (PubMed:28500257; PubMed:28082411). Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming; a process that prevents the accumulation of aberrantly long telomeres (PubMed:28082411). Also acts as a transcription regulator that binds to promoter regions (PubMed:7969177; PubMed:24382891; PubMed:28500257). Regulates expression of a small subset of genes; including MTFP1 (PubMed:28500257). Regulates expression the J and/or S elements in MHC II promoter (PubMed:7969177). Acts as a negative regulator of cell proliferation by specifically activating expression of ARF; a tumor suppressor isoform of CDKN2A (PubMed:24382891).
- Gene Details:
- zinc finger and BTB domain containing 48
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Telomere zinc finger-associated protein (1-280AA)
- Isotype:
- IgG
- Protein Details:
- Telomere zinc finger-associated protein
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
