ARIH2 Antibody
Product Sizes
50ul
£316.00
OACA08288-50UL
100ul
£387.00
OACA08288-100UL
About this Product
- SKU:
- OACA08288
- Additional Names:
- all-trans retinoic acid inducible RING finger;ARI2;ariadne homolog 2;E3 ubiquitin-protein ligase ARIH2;protein ariadne-2 homolog;RING-type E3 ubiquitin transferase ARIH2;TRIAD1;Triad1 protein.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- E3 ubiquitin-protein ligase; which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3 (PubMed:16118314; PubMed:17646546; PubMed:19340006; PubMed:24076655). Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-5-RING ubiquitin ligase complex (ECS complex; also named CRL5 complex) and initiating ubiquitination of ECS substrates: associates with ECS complex and specifically mediates addition of the first ubiquitin on ECS targets (By similarity). The initial ubiquitin is then elongated (By similarity). E3 ubiquitin-protein ligase activity is activated upon binding to neddylated form of the ECS complex (PubMed:24076655). Mediates 'Lys-6'; 'Lys-48'-and 'Lys-63'-linked polyubiquitination (PubMed:16118314; PubMed:17646546; PubMed:19340006). May play a role in myelopoiesis (PubMed:19340006).
- Gene Details:
- ariadne RBR E3 ubiquitin protein ligase 2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human E3 ubiquitin-protein ligase ARIH2 protein (194-493AA)
- Isotype:
- IgG
- Protein Details:
- E3 ubiquitin-protein ligase ARIH2
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
