UPF2 Antibody
Product Sizes
50ul
£316.00
OACA08214-50UL
100ul
£387.00
OACA08214-100UL
About this Product
- SKU:
- OACA08214
- Additional Names:
- FRS2/UPF2/LEMD3 fusion;HUPF2;LEMD3/UPF2 fusion;nonsense mRNA reducing factor 2;regulator of nonsense transcripts 2;RENT2;smg-3;smg-3 homolog; nonsense mediated mRNA decay factor;UPF2 regulator of nonsense transcripts homolog;up-frameshift suppressor 2 homolog;yeast Upf2p homolog.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA.
- Gene Details:
- UPF2 regulator of nonsense mediated mRNA decay
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Regulator of nonsense transcripts 2 protein (1153-1272AA)
- Isotype:
- IgG
- Protein Details:
- Regulator of nonsense transcripts 2
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
