ANAPC2 Antibody
Product Sizes
50ul
£316.00
OACA08168-50UL
100ul
£387.00
OACA08168-100UL
About this Product
- SKU:
- OACA08168
- Additional Names:
- anaphase-promoting complex subunit 2;APC2;cyclosome subunit 2.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Together with the RING-H2 protein ANAPC11; constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C); a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and; to a lower extent; the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.
- Gene Details:
- anaphase promoting complex subunit 2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Anaphase-promoting complex subunit 2 protein (1-230AA)
- Isotype:
- IgG
- Protein Details:
- Anaphase-promoting complex subunit 2
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
