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Antibodies

ZC3HC1 Antibody

Product Sizes
50ul
£316.00
OACA07933-50UL
100ul
£387.00
OACA07933-100UL
About this Product
SKU:
OACA07933
Additional Names:
hematopoietic stem/progenitor cell protein 216;HSPC216;NIPA;nuclear interacting partner of anaplastic lymphoma kinase (ALK);nuclear-interacting partner of ALK;Nuclear-interacting partner of anaplastic lymphoma kinase;Zinc finger C3HC-type protein 1.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Essential component of a SCF-type E3 ligase complex; SCF(NIPA); a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex; restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
Gene Details:
zinc finger C3HC-type containing 1
Host:
Rabbit
Immunogen:
Recombinant Human Nuclear-interacting partner of ALK protein (1-260AA)
Isotype:
IgG
Protein Details:
Nuclear-interacting partner of ALK
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody