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Antibodies

CIAPIN1 Antibody

Product Sizes
50ul
£316.00
OACA07918-50UL
100ul
£387.00
OACA07918-100UL
About this Product
SKU:
OACA07918
Additional Names:
anamorsin;CIAE2;Cytokine-induced apoptosis inhibitor 1;DRE2;fe-S cluster assembly protein DRE2 homolog;predicted protein of HQ0915;PRO0915.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis; facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1 (PubMed:23596212). NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR); probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity).
Gene Details:
cytokine induced apoptosis inhibitor 1
Host:
Rabbit
Immunogen:
Recombinant Human Anamorsin protein (1-312AA)
Isotype:
IgG
Protein Details:
Anamorsin
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody