LITAF Antibody
Product Sizes
50ul
£316.00
OACA07878-50UL
100ul
£387.00
OACA07878-100UL
About this Product
- SKU:
- OACA07878
- Additional Names:
- lipopolysaccharide-induced TNF-alpha factor;lipopolysaccharide-induced tumor necrosis factor-alpha factor;LPS-induced TNF-alpha factor;p53-induced gene 7 protein;PIG7;SIMPLE;small integral membrane protein of lysosome/late endosome;TP53I7;tumor protein p53 inducible protein 7.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Plays a role in endosomal protein trafficking and in targeting proteins for lysosomal degradation (PubMed:23166352). Plays a role in targeting endocytosed EGFR and ERGG3 for lysosomal degradation; and thereby helps downregulate downstream signaling cascades (PubMed:23166352). Helps recruit the ESCRT complex components TSG101; HGS and STAM to cytoplasmic membranes (PubMed:23166352). Probably plays a role in regulating protein degradation via its interaction with NEDD4 (PubMed:15776429). May also contribute to the regulation of gene expression in the nucleus (PubMed:10200294; PubMed:15793005). Binds DNA (in vitro) and may play a synergistic role with STAT6 in the nucleus in regulating the expression of various cytokines (PubMed:15793005). May regulate the expression of numerous cytokines; such as TNF; CCL2; CCL5; CXCL1; IL1A and IL10 (PubMed:10200294; PubMed:15793005).
- Gene Details:
- lipopolysaccharide induced TNF factor
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Lipopolysaccharide-induced tumor necrosis factor-alpha factor protein (1-161AA)
- Isotype:
- IgG
- Protein Details:
- Lipopolysaccharide-induced tumor necrosis factor-alpha factor
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
