Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

SF3B3 Antibody

Product Sizes
50ul
£316.00
OACA07736-50UL
100ul
£387.00
OACA07736-100UL
About this Product
SKU:
OACA07736
Additional Names:
pre-mRNA splicing factor SF3b; 130 kDa subunit;Pre-mRNA-splicing factor SF3b 130 kDa subunit;RSE1;SAP 130;SAP130;SF3b130;spliceosome-associated protein 130;splicing factor 3B subunit 3;STAF130.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex; a constituent of the spliceosome (PubMed:10490618; PubMed:10882114; PubMed:27720643; PubMed:28781166). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential; it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937). May also be involved in the assembly of the 'E' complex (PubMed:10882114). Belongs also to the minor U12-dependent spliceosome; which is involved in the splicing of rare class of nuclear pre-mRNA intron (PubMed:15146077).
Gene Details:
splicing factor 3b subunit 3
Host:
Rabbit
Immunogen:
Recombinant Human Splicing factor 3B subunit 3 protein (948-1217AA)
Isotype:
IgG
Protein Details:
Splicing factor 3B subunit 3
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody