TOPBP1 Antibody
Product Sizes
50ul
£316.00
OACA07722-50UL
100ul
£387.00
OACA07722-100UL
About this Product
- SKU:
- OACA07722
- Additional Names:
- DNA topoisomerase 2-binding protein 1;DNA topoisomerase II-beta-binding protein 1;DNA topoisomerase II-binding protein 1;Dpb11;TOP2BP1;topoisomerase (DNA) II binding protein 1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Required for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR (PubMed:16530042).
- Gene Details:
- DNA topoisomerase II binding protein 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DNA topoisomerase 2-binding protein 1 protein (1253-1522AA)
- Isotype:
- IgG
- Protein Details:
- DNA topoisomerase 2-binding protein 1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
