HSPA2 Antibody
Product Sizes
50ul
£316.00
OACA07644-50UL
100ul
£387.00
OACA07644-100UL
About this Product
- SKU:
- OACA07644
- Additional Names:
- epididymis secretory sperm binding protein;heat shock 70kD protein 2;heat shock 70kDa protein 2;heat shock-related 70 kDa protein 2;HSP70-2;HSP70-3.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Molecular chaperone implicated in a wide variety of cellular processes; including protection of the proteome from stress; folding and transport of newly synthesized polypeptides; activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system; ensuring the correct folding of proteins; the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding; ATP hydrolysis and ADP release; mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form; it has a low affinity for substrate proteins. However; upon hydrolysis of the ATP to ADP; it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange; which permits cycles of substrate binding and release (PubMed:26865365). Plays a role in spermatogenesis. In association with SHCBP1L may participate in the maintenance of spindle integrity during meiosis in male germ cells (By similarity).
- Gene Details:
- heat shock protein family A (Hsp70) member 2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Heat shock-related 70 kDa protein 2 protein (400-639AA)
- Isotype:
- IgG
- Protein Details:
- Heat shock-related 70 kDa protein 2
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
