IFNL3 Antibody
Product Sizes
50ul
£316.00
OACA07600-50UL
100ul
£387.00
OACA07600-100UL
About this Product
- SKU:
- OACA07600
- Additional Names:
- cytokine Zcyto22;IFN-lambda-3;IFN-lambda-4;IL28B;IL-28B;IL28C;IL-28C;interferon lambda-3;interferon; lambda 4;interleukin-28B;interleukin-28C.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Cytokine with antiviral; antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense; predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1; and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG); which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection; but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
- Gene Details:
- interferon lambda 3
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Interferon lambda-3 protein (22-196AA)
- Isotype:
- IgG
- Protein Details:
- Interferon lambda-3
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
