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Antibodies

IFNL1 Antibody

Product Sizes
50ul
£316.00
OACA07590-50UL
100ul
£387.00
OACA07590-100UL
About this Product
SKU:
OACA07590
Additional Names:
cytokine Zcyto21;IFN-lambda-1;IL29;IL-29;interferon lambda-1;interleukin 29 (interferon; lambda 1);interleukin-29.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Cytokine with antiviral; antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense; predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1; and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG); which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Gene Details:
interferon lambda 1
Host:
Rabbit
Immunogen:
Recombinant Human Interferon lambda-1 protein (20-200AA)
Isotype:
IgG
Protein Details:
Interferon lambda-1
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody