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Antibodies

AKAP10 Antibody

Product Sizes
50ul
£316.00
OACA07492-50UL
100ul
£387.00
OACA07492-100UL
About this Product
SKU:
OACA07492
Additional Names:
A kinase (PRKA) anchor protein 10;AKAP-10;A-kinase anchor protein 10; mitochondrial;D-AKAP2;D-AKAP-2;dual specificity A kinase-anchoring protein 2;mitochondrial A kinase PPKA anchor protein 10;PRKA10;protein kinase A anchoring protein 10;Protein kinase A-anchoring protein 10.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood; one idea is that BAD; a proapoptotic member; is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction; by acting as an adapter for assembling multiprotein complexes. With its RGS domain; it could lead to the interaction to G-alpha proteins; providing a link between the signaling machinery and the downstream kinase (By similarity).
Gene Details:
A-kinase anchoring protein 10
Host:
Rabbit
Immunogen:
Recombinant Human A-kinase anchor protein 10; mitochondrial protein (413-662AA)
Isotype:
IgG
Protein Details:
A-kinase anchor protein 10; mitochondrial
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody