ASNA1 Antibody
Product Sizes
50ul
£316.00
OACA07467-50UL
100ul
£387.00
OACA07467-100UL
About this Product
- SKU:
- OACA07467
- Additional Names:
- arsA arsenite transporter; ATP-binding; homolog 1;ARSA1;ARSA-I;Arsenical pump-driving ATPase;Arsenite-stimulated ATPase;ASNA1;ASNA-I;ATPase GET3;golgi to ER traffic 3 homolog;hARSA-I;hASNA-I;transmembrane domain recognition complex 40 kDa ATPase subunit;TRC40.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors; where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state; facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently; the homodimer reverts towards the open dimer state; lowering its affinity for the membrane-bound receptor; and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.
- Gene Details:
- guided entry of tail-anchored proteins factor 3; ATPase
- Host:
- Rabbit
- Immunogen:
- Recombinant Human ATPase ASNA1 protein (1-348AA)
- Isotype:
- IgG
- Protein Details:
- ATPase ASNA1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
