BMX Antibody
Product Sizes
50ul
£316.00
OACA07371-50UL
100ul
£387.00
OACA07371-100UL
About this Product
- SKU:
- OACA07371
- Additional Names:
- bone marrow tyrosine kinase gene in chromosome X protein;BTK-like on X chromosome;cytoplasmic tyrosine-protein kinase BMX;epithelial and endothelial tyrosine kinase;ETK;Etk/Bmx cytosolic tyrosine kinase;NTK38;NTK38 tyrosine kinase;PSCTK2;PSCTK3.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization; cell migration; cell proliferation and survival; cell adhesion; and apoptosis. Participates in signal transduction stimulated by growth factor receptors; cytokine receptors; G-protein coupled receptors; antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1; a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility. Plays a critical role in TNF-induced angiogenesis; and implicated in the signaling of TEK and FLT1 receptors; 2 important receptor families essential for angiogenesis. Required for the phosphorylation and activation of STAT3; a transcription factor involved in cell differentiation. Also involved in interleukin-6 (IL6) induced differentiation. Plays also a role in programming adaptive cytoprotection against extracellular stress in different cell systems; salivary epithelial cells; brain endothelial cells; and dermal fibroblasts. May be involved in regulation of endocytosis through its interaction with an endosomal protein RUFY1. May also play a role in the growth and differentiation of hematopoietic cells; as well as in signal transduction in endocardial and arterial endothelial cells.
- Gene Details:
- BMX non-receptor tyrosine kinase
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Cytoplasmic tyrosine-protein kinase BMX protein (65-280AA)
- Isotype:
- IgG
- Protein Details:
- Cytoplasmic tyrosine-protein kinase BMX
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
