TDP1 Antibody
Product Sizes
50ul
£316.00
OACA07257-50UL
100ul
£387.00
OACA07257-100UL
About this Product
- SKU:
- OACA07257
- Additional Names:
- tyr-DNA phosphodiesterase 1;tyrosyl-DNA phosphodiesterase 1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond; giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3'phosphate.
- Gene Details:
- tyrosyl-DNA phosphodiesterase 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Tyrosyl-DNA phosphodiesterase 1 protein (1-260AA)
- Isotype:
- IgG
- Protein Details:
- Tyrosyl-DNA phosphodiesterase 1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
