CISH Antibody
Product Sizes
50ul
£316.00
OACA07135-50UL
100ul
£387.00
OACA07135-100UL
About this Product
- SKU:
- OACA07135
- Additional Names:
- BACTS2;CIS;CIS-1;cytokine-inducible inhibitor of signaling type 1B;cytokine-inducible SH2-containing protein;G18;Protein G18;SOCS;suppressor of cytokine signaling.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin; prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
- Gene Details:
- cytokine inducible SH2 containing protein
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Cytokine-inducible SH2-containing protein (1-257AA)
- Isotype:
- IgG
- Protein Details:
- Cytokine-inducible SH2-containing protein
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
