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Antibodies

IL1R2 Antibody

Product Sizes
50ul
£316.00
OACA07087-50UL
100ul
£387.00
OACA07087-100UL
About this Product
SKU:
OACA07087
Additional Names:
antigen CDw121b;CD121 antigen-like family member B;CD121b;CDw121b;IL-1 type II receptor;IL-1R-2;IL1R2c;IL1RB;IL-1R-beta;IL-1RT2;IL-1RT-2;interleukin 1 receptor type II variant 3;interleukin-1 receptor beta;interleukin-1 receptor type 2;interleukin-1 receptor type II;type II interleukin-1 receptor; beta.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Non-signaling receptor for IL1A; IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Gene Details:
interleukin 1 receptor type 2
Host:
Rabbit
Immunogen:
Recombinant Human Interleukin-1 receptor type 2 protein (20-320AA)
Isotype:
IgG
Protein Details:
Interleukin-1 receptor type 2
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody