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Antibodies

PARP3 Antibody

Product Sizes
50ul
£316.00
OACA07071-50UL
100ul
£387.00
OACA07071-100UL
About this Product
SKU:
OACA07071
Additional Names:
ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2;ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 3;ADP-ribosyltransferase diphtheria toxin-like 3;ADPRT3;ADPRT-3;ADPRTL2;ADPRTL3;ARTD3;DNA ADP-ribosyltransferase PARP3;IRT1;NAD(+) ADP-ribosyltransferase 3;NAD+ ADP-ribosyltransferase 3;PADPRT-3;poly [ADP-ribose] polymerase 3;poly(ADP-ribose) synthetase-3;poly[ADP-ribose] synthase 3;poly[ADP-ribose] synthetase 3;protein mono-ADP-ribosyltransferase PARP3.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Involved in the base excision repair (BER) pathway; by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
Gene Details:
poly(ADP-ribose) polymerase family member 3
Host:
Rabbit
Immunogen:
Recombinant Human Poly [ADP-ribose] polymerase 3 protein (294-533AA)
Isotype:
IgG
Protein Details:
Poly [ADP-ribose] polymerase 3
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody