SRSF1 Antibody
Product Sizes
50ul
£316.00
OACA07055-50UL
100ul
£387.00
OACA07055-100UL
About this Product
- SKU:
- OACA07055
- Additional Names:
- alternative-splicing factor 1;ASF;pre-mRNA-splicing factor SF2; P33 subunit;serine/arginine-rich splicing factor 1;SF2;SF2p33;SFRS1;splicing factor 2;Splicing factor; arginine/serine-rich 1;splicing factor; arginine/serine-rich; 30-KD; A;SR splicing factor 1;SRp30a.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Plays a role in preventing exon skipping; ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components; via the RS domains; to form a bridge between the 5'- and 3'-splice site binding components; U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences; either the octamer; 5'-RGAAGAAC-3' (r=A or G) or the decamers; AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octamer constitute a powerful splicing enhancer in vitro; the ASF/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing. Isoform ASF-2 and isoform ASF-3 act as splicing repressors. May function as export adapter involved in mRNA nuclear export through the TAP/NXF1 pathway.
- Gene Details:
- serine and arginine rich splicing factor 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Serine/arginine-rich splicing factor 1 protein (1-248AA)
- Isotype:
- IgG
- Protein Details:
- Serine/arginine-rich splicing factor 1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
