TARDBP Antibody
Product Sizes
50ul
£316.00
OACA07038-50UL
100ul
£387.00
OACA07038-100UL
About this Product
- SKU:
- OACA07038
- Additional Names:
- ALS10;TAR DNA-binding protein 43;TAR DNA-binding protein-43;TDP-43.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis; apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.
- Gene Details:
- TAR DNA binding protein
- Host:
- Rabbit
- Immunogen:
- Recombinant Human TAR DNA-binding protein 43 protein (1-260AA)
- Isotype:
- IgG
- Protein Details:
- TAR DNA-binding protein 43
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
