IL1R1 Antibody
Product Sizes
50ul
£316.00
OACA07017-50UL
100ul
£387.00
OACA07017-100UL
About this Product
- SKU:
- OACA07017
- Additional Names:
- CD121 antigen-like family member A;CD121A;D2S1473;IL1R;IL-1R-1;IL1RA;IL-1R-alpha;IL-1RT1;IL-1RT-1;interleukin 1 receptor alpha; type I;interleukin-1 receptor alpha;interleukin-1 receptor type 1;interleukin-1 receptor type I;P80.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Receptor for IL1A; IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B; MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP; MYD88; and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (PubMed:10653850).
- Gene Details:
- interleukin 1 receptor type 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Interleukin-1 receptor type 1 protein (18-320AA)
- Isotype:
- IgG
- Protein Details:
- Interleukin-1 receptor type 1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
