TNFSF18 Antibody
Product Sizes
50ul
£316.00
OACA06956-50UL
100ul
£387.00
OACA06956-100UL
About this Product
- SKU:
- OACA06956
- Additional Names:
- activation-inducible TNF-related ligand;AITR ligand;AITRL;GITR ligand;GITRL;glucocorticoid-induced TNF-related ligand;glucocorticoid-induced TNFR-related protein ligand;hGITRL;TL6;TNLG2A;tumor necrosis factor (ligand) superfamily; member 18;tumor necrosis factor ligand 2A;tumor necrosis factor ligand superfamily member 18;tumor necrosis factor superfamily member 18.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation (By similarity).
- Gene Details:
- TNF superfamily member 18
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Tumor necrosis factor ligand superfamily member 18 protein (72-199AA)
- Isotype:
- IgG
- Protein Details:
- Tumor necrosis factor ligand superfamily member 18
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
