ALKBH8 Antibody
Product Sizes
50ul
£316.00
OACA06810-50UL
100ul
£387.00
OACA06810-100UL
About this Product
- SKU:
- OACA06810
- Additional Names:
- ABH8;AlkB homologue 8;alkB; alkylation repair homolog 8;alkylated DNA repair protein alkB homolog 8;MRT71;probable alpha-ketoglutarate-dependent dioxygenase ABH8;S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8;TRM9;TRMT9;TRMT9A;tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8;tRNA methyltransferase 9 homolog;tRNA methyltransferase 9 related.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain (PubMed:20123966; PubMed:20308323). Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA (PubMed:20123966; PubMed:20308323). Has a preference for tRNA(Arg) and tRNA(Glu); and does not bind tRNA(Lys)(PubMed:20308323). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain; giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly) (PubMed:21285950). Required for normal survival after DNA damage (PubMed:20308323). May inhibit apoptosis and promote cell survival and angiogenesis (PubMed:19293182).
- Gene Details:
- alkB homolog 8; tRNA methyltransferase
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Alkylated DNA repair protein alkB homolog 8 protein (1-230AA)
- Isotype:
- IgG
- Protein Details:
- Alkylated DNA repair protein alkB homolog 8
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
