CD274 Antibody
Product Sizes
50ul
£316.00
OACA06799-50UL
100ul
£387.00
OACA06799-100UL
About this Product
- SKU:
- OACA06799
- Additional Names:
- B7 homolog 1;B7-H;B7H1;CD274 antigen;hPD-L1;PDCD1 ligand 1;PDCD1L1;PDCD1LG1;PDL1;PD-L1;programmed cell death 1 ligand 1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279; modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (PubMed:28813417; PubMed:28813410). Through a yet unknown activating receptor; may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (PubMed:10581077).
- Gene Details:
- CD274 molecule
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Programmed cell death 1 ligand 1 protein (19-238AA)
- Isotype:
- IgG
- Protein Details:
- Programmed cell death 1 ligand 1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
