BNIP3 Antibody
Product Sizes
50ul
£316.00
OACA06713-50UL
100ul
£387.00
OACA06713-100UL
About this Product
- SKU:
- OACA06713
- Additional Names:
- BCL2/adenovirus E1B 19 kDa protein-interacting protein 3;BCL2/adenovirus E1B 19kDa interacting protein 3;BCL2/adenovirus E1B interacting protein 3;nineteen kD interacting protein-3;NIP3.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage; participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP; BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway.
- Gene Details:
- BCL2 interacting protein 3
- Host:
- Rabbit
- Immunogen:
- Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 protein (1-164AA)
- Isotype:
- IgG
- Protein Details:
- BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
